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      Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema – Research

      Xiao et al. identify α-KG as a rosacea-associated metabolite that activates the OXGR1-Gq-MYL9 axis in the vascular smooth muscle cells to boost contractility and suppress pathological vasodilation underlying erythema. Cryo-EM reveals a bipartite-acid pocket...

      Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema – Research

      Xiao et al. identify α-KG as a rosacea-associated metabolite that activates the OXGR1-Gq-MYL9 axis in the vascular smooth muscle cells to boost contractility and...

      Somatic genomics as a discovery engine for biomedicine – Research

      Somatic genetics uses tissue mutations to understand aging, reveal disease mechanisms, and guide new therapies. Read more about this post... Credits: Source Disclaimer

      Tufts launches faculty pay transparency initiative following Massachusetts transparency law – The Tufts Daily – Open Positions

      Tufts launches faculty pay transparency initiative following Massachusetts transparency law  The Tufts Daily Read more about his post... Credits: Source Disclaimer

      Administrative Operations Coordinator – Open Positions

      University of Kentucky (Lexington, KY) Read more about his post... Credits: Source Disclaimer

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      Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema – Research

      Xiao et al. identify α-KG as a rosacea-associated metabolite that activates the OXGR1-Gq-MYL9 axis in the vascular smooth muscle cells to boost contractility and...

      Somatic genomics as a discovery engine for biomedicine – Research

      Somatic genetics uses tissue mutations to understand aging, reveal disease mechanisms, and guide new therapies. Read more about this post... Credits: Source Disclaimer

      Tufts launches faculty pay transparency initiative following Massachusetts transparency law – The Tufts Daily – Open Positions

      Tufts launches faculty pay transparency initiative following Massachusetts transparency law  The Tufts Daily Read more about his post... Credits: Source Disclaimer

      Administrative Operations Coordinator – Open Positions

      University of Kentucky (Lexington, KY) Read more about his post... Credits: Source Disclaimer
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